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The conundrum of the α5 nicotinic acetylcholine receptor subunit

✍ Scribed by Sonia Bertrand; Estelle Neveu; Daniel Bertrand; Cecilia Gotti

Book ID
113489557
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
259 KB
Volume
82
Category
Article
ISSN
0006-2952

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Nicotinic acetylcholine receptors (nAChRs) are ligand-gated pentameric cation channels of alpha and beta subunits. The alpha5 subunit, when added to heteromeric complexes, alters pharmacological and physiological properties of nAChRs, which may be important during development. Here we have evaluated