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Nicotinic acetylcholine receptor α5 subunits modulate oxotremorine-induced salivation and tremor

✍ Scribed by Ningshan Wang; Avi Orr-Urtreger; Joab Chapman; Ruth Rabinowitz; Amos D Korczyn

Book ID
119301424
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
220 KB
Volume
222
Category
Article
ISSN
0022-510X

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✍ Ursula H. Winzer-Serhan; Frances M. Leslie 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 708 KB

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated pentameric cation channels of alpha and beta subunits. The alpha5 subunit, when added to heteromeric complexes, alters pharmacological and physiological properties of nAChRs, which may be important during development. Here we have evaluated