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The contribution of homologous recombination in preserving genome integrity in mammalian cells

โœ Scribed by Larry H Thompson; David Schild


Book ID
117457230
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
602 KB
Volume
81
Category
Article
ISSN
0300-9084

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Genome instability has been associated with progression of transformed cells to high tumorigenicity. Although genome instability may result from a variety of factors, some studies suggest that DNA in the region of a chromosome rearrangement can subsequently have much higher rates of DNA deletions or