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The conformation of angiotensin II: II. The rates of peptide NH exchange with solvent for [Asn1, Val5]angiotensin II, angiotensin III and saralasin

✍ Scribed by Robert E. Lenkinski; Richard L. Stephens; N. Rama Krishna


Book ID
113126571
Publisher
Elsevier Science
Year
1981
Weight
678 KB
Volume
667
Category
Article
ISSN
0005-2795

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Synthesis of [Sar1, Val5, (4β€²-Azido-3β€²,5
✍ Michel Bernier; Emannuel Escher πŸ“‚ Article πŸ“… 1980 πŸ› John Wiley and Sons 🌐 German βš– 219 KB πŸ‘ 1 views

## Abstract The synthesis of [Sar^1^, Val^5^, (4′‐azido‐3β€²,5′‐ditritio)Phe^8^] angiotensin II from a iodinated precursor peptide is described. The principal problems of this synthesis and their resolution are discussed: (i) The β‐induced autophotolysis of the highly tritiated (73 Ci/mmol) and photo