𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The complexity of targeting EGFR signalling in cancer: From expression to turnover

✍ Scribed by Sinto Sebastian; Jeffrey Settleman; Stephan J. Reshkin; Amalia Azzariti; Antonia Bellizzi; Angelo Paradiso

Book ID
113486632
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
654 KB
Volume
1766
Category
Article
ISSN
0304-419X

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Additional value of EGFR downstream sign
Additional value of EGFR downstream signaling phosphoprotein expression to KRAS status for response to anti-EGFR antibodies in colorectal cancer
✍ Geraldine Perkins; Astrid LiΓ¨vre; Carole Ramacci; Tchao MΓ©atchi; AurΓ©lien de Rey πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 393 KB

## Abstract __KRAS__ mutations are a strong predictive marker of resistance to anti‐epidermal growth factor receptor (EGFR) antibodies in advanced colorectal cancer (CRC) but only a subset of wild‐type (WT) __KRAS__ patients are responders, suggesting the existence of additional markers of resistan

Drugs for HER-2-positive Breast Cancer V
Drugs for HER-2-positive Breast Cancer Volume 7 || The EGFR/ErbB Family in Breast Cancer: From Signalling to Therapy
✍ Sibilia, Maria; Zielinski, Christoph C.; Bartsch, Rupert; Grunt, Thomas W. πŸ“‚ Article πŸ“… 2010 πŸ› Springer Basel 🌐 German βš– 425 KB

Growth factor receptors have long been known to drive malignant transformation and cancer progression. The epidermal growth factor receptor (EGFR, ErbB, HER) system is likely the best described membrane receptor tyrosine kinase family in malignant tumors. With implementation of the growth-inhibitory