Expression of microsomal prostaglandin E
✍
Bastiaan P. van Rees; Anna Sivula; Staffan Thorén; Hiroshi Yokozaki; Per-Johan J
📂
Article
📅
2003
🏛
John Wiley and Sons
🌐
French
⚖ 317 KB
Gastrointestinal carcinomas synthesize elevated levels of prostaglandin E(2) (PGE(2)), which has been mechanistically linked to carcinogenesis. Recently, microsomal prostaglandin E synthase-1 (mPGES-1) was cloned, which seems to be inducible and linked to cyclooxygenase-2 (Cox-2) in the biosynthesis