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The complexity of reproductive decision-making in asymptomatic carriers of the Huntington mutation

✍ Scribed by Decruyenaere, Marleen; Evers-Kiebooms, Gerry; Boogaerts, Andrea; Philippe, Kristien; Demyttenaere, Koen; Dom, René; Vandenberghe, Wim; Fryns, Jean-Pierre

Book ID
110026875
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
118 KB
Volume
15
Category
Article
ISSN
1018-4813

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## Abstract Huntington's disease (HD) is an autosomal dominantly inherited neurodegenerative disorder caused by a CAG repeat expansion in the __IT‐15__ gene; however, it remains unknown how the mutation leads to selective neurodegeneration. Several lines of evidence suggest impaired mitochondrial f