✦ LIBER ✦

The companions: regulatory T cells and gene therapy

✍ Scribed by Saman Eghtesad; Penelope A. Morel; Paula R. Clemens

Book ID: 108782542
Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 143 KB
Volume: 127
Category: Article
ISSN: 0019-2805
DOI: 10.1111/j.1365-2567.2009.03069.x

No coin nor oath required. For personal study only.

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## Abstract CD4^+^CD25^+^ regulatory T cells (Treg) appear to be critical in regulating immune responses to self‐antigens. Treg deficiency is associated with several human autoimmune diseases. Although substantial progress has been made in the study of murine and human Treg, their fundamental mecha