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The combination of ursodeoxycholic acid and methotrexate for patients with primary biliary cirrhosis: The results of a pilot study*1

✍ Scribed by LINDOR, K


Book ID
121941569
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
545 KB
Volume
22
Category
Article
ISSN
0270-9139

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The combination of ursodeoxycholic acid
✍ Keith D. Lindor; E. Rolland Dickson; Roberta A. Jorgensen; Monte L. Anderson; Ru πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 553 KB

Ursodeoxycholic acid (UDCA) and methotrexate (MTX) have both been proposed as treatments for patients with primary biliary cirrhosis (PBC). It has been suggested that a combination of the two drugs may offer advantages over either used separately. In this pilot study, we sought to evaluate the safet

Methotrexate (MTX) plus ursodeoxycholic
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This placebo-controlled, randomized, multicenter trial compared the effects of MTX plus UDCA to UDCA alone on the course of primary biliary cirrhosis (PBC). Two hundred and sixty five AMA positive patients without ascites, variceal bleeding, or encephalopathy; a serum bilirubin less than 3 mg/dL; se