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The Co-chaperone Sba1 Connects the ATPase Reaction of Hsp90 to the Progression of the Chaperone Cycle

โœ Scribed by Klaus Richter; Stefan Walter; Johannes Buchner


Book ID
116661524
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
580 KB
Volume
342
Category
Article
ISSN
0022-2836

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## Abstract Activation of the Hsp90 chaperone system is a characteristic of cancer cells. The regulation of chaperone activities involves their interaction with cochaperones; therefore we investigated the expression of Hsp70 and Hsp90 and their specific co-chaperones HOP and CHIP in cancer cell lin