𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The clinical utility of randomized controlled trials

✍ Scribed by Wilson, G. Terence


Publisher
Wiley (John Wiley & Sons)
Year
1998
Tongue
English
Weight
167 KB
Volume
24
Category
Article
ISSN
0276-3478

No coin nor oath required. For personal study only.

✦ Synopsis


Objective: Efficacy studies using randomized controlled trials (RCTs), on which empirically supported treatments are based, are often rejected as having little if any relevance to clinical practice. RCTs are faulted for allegedly excluding poor prognosis patients and therapists and treatments that are unrepresentative of clinical practice. Methods: Evidence on the generalizability of findings from RCTs to diverse patient populations, different therapists, and varied clinical settings is critically evaluated. Results: Existing research indicates that RCTs commonly include patients with multiple problems and levels of disturbance as severe as patients in clinical settings. Discussion: The applicability of the findings of RCTs to clinical practice will be a changing function of the nature of the particular study and clinical setting to which the results are to be generalized. Future research should address the clinical utility of the findings of efficacy studies across different patient populations, therapists, and treatment methods.


πŸ“œ SIMILAR VOLUMES


Rationale, objectives, and interpretatio
✍ Eleftherios C. Vamvakas πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 58 KB πŸ‘ 1 views

A randomized controlled trial (RCT) is the most definitive tool for evaluation of the effectiveness of an intervention and can establish a cause-and-effect relationship between an intervention and an improved disease outcome. However, the undertaking of an RCT does not guarantee valid results, and t

Esophageal cancer surgery: The value of
✍ Simon Y. Law; John Wong πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 42 KB πŸ‘ 2 views

Prospective randomized controlled trials (RCT) in esophageal cancer were reviewed. Their value and significance in the areas of multimodality therapy, lymphadenectomy, surgical techniques, palliative treatments, and perioperative management were evaluated. Much has been gained through RCT in the man

Randomized clinical trial of antibiotic
✍ Brian C. Brost; Barry Campbell; Sue Stamm; Daniel Eller; Roger B. Newman πŸ“‚ Article πŸ“… 1996 πŸ› Hindawi Publishing Corporation 🌐 English βš– 81 KB πŸ‘ 1 views

Objective: The aim of this study was to prospectively evaluate the efficacy of a therapeutic course of intravenous antibiotics followed by oral antibiotics vs. intravenous antibiotics alone to prevent recurrent urinary tract infection. Methods: Pyelonephritis was documented by strict criteria in 67