✦ LIBER ✦

Esophageal cancer surgery: The value of controlled clinical trials

✍ Scribed by Simon Y. Law; John Wong

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 42 KB
Volume: 13
Category: Article
ISSN: 8756-0437
DOI: 10.1002/(sici)1098-2388(199707/08)13:4<281::aid-ssu10>3.0.co;2-v

No coin nor oath required. For personal study only.

✦ Synopsis

Prospective randomized controlled trials (RCT) in esophageal cancer were reviewed. Their value and significance in the areas of multimodality therapy, lymphadenectomy, surgical techniques, palliative treatments, and perioperative management were evaluated. Much has been gained through RCT in the management of esophageal cancer, and RCT is the most reliable scientific method in clinical investigations. Problems in the conduct of such trials include lack of expertise by surgeons, lack of patients, lack of funding, and methodologic and ethical problems. These obstacles could be overcome and more well-conducted RCTs encouraged.

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