The clinical significance of reactivity to individual epitopes of the hepatitis C viral genome
β Scribed by Yatsuhashi, Hiroshi ;Inokuchi, Kaoru ;Inoue, Osami ;Matsumura, Nobuyuki ;Koga, Michiaki ;Kosakai, Yukari ;Yano, Michitami
- Book ID
- 105677972
- Publisher
- Springer-Verlag
- Year
- 1993
- Tongue
- English
- Weight
- 588 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0435-1339
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Although HBV has a circular DNA genome that is partially double stranded, it replicates by means of an RNA intermediate. The process is catalyzed by a translation product of the polymerase open reading frame that has reverse transcriptase activity. The enzyme is
## Abstract Most patients with an acute infection of hepatitis C virus (HCV) will develop chronic hepatitis, and only about 15β20% of the cases will resolve spontaneously. The mechanism for the different outcomes in patients with acute HCV infection remains unclear. HCV genotype has been recognized