## Abstract Chronic hepatitis B infection is a major cause of hepatocellular cancer (HCC). The pathogenesis of the carcinogenesis is not fully understood. Viral proteins such as the X protein and the truncated middle S protein have been implicated to be transactivators. In order to investigate whet
The clinical significance of molecular variation within the hepatitis B virus genome
β Scribed by Jonathan L. Brown; William F. Carman; Howard C. Thomas
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 648 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
β¦ Synopsis
Although HBV has a circular DNA genome that is partially double stranded, it replicates by means of an RNA intermediate. The process is catalyzed by a translation product of the polymerase open reading frame that has reverse transcriptase activity. The enzyme is
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