The clinical significance of Fas expression in leukemia: questions and controversies
β Scribed by Findley, H W; Zhou, M
- Book ID
- 110054081
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 61 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0887-6924
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CD7 antigen, a T-cell lineage associated antigen, is expressed in a minority of patients with acute myeloid leukemia (AML). The biologic and clinical significance of this finding is not clearly established. In this retrospective study of patients with de novo acute myeloid leukemia, we have identifi
## Fas (Apo-1/CD95 ) is a cell membrane receptor involved in apoptotic cell death. Soluble variant forms (sFas) lacking the transmembrane domain due to alternative splicing have been identified. Up-regulation of sFas expression is reportedly implicated in prereceptorial blockage of Fas-induced apo