Expression of survivin, CDK4, Ki-67 and clinical significance in pediatric acute leukemia
β Scribed by Liuqing Zhang; Jing Liu; Hanhua Lin; Qun Hu; Aiguo Liu; Ying Hu
- Book ID
- 107405437
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- Chinese
- Weight
- 58 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0510-9752
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CD7 antigen, a T-cell lineage associated antigen, is expressed in a minority of patients with acute myeloid leukemia (AML). The biologic and clinical significance of this finding is not clearly established. In this retrospective study of patients with de novo acute myeloid leukemia, we have identifi
## Abstract Survivin, a member of the inhibitor of apoptosis protein family, is expressed in most human cancers, but undetectable in normal differentiated adult tissue __in vivo__. Because of this cancerβrelated expression, survivin is a promising target for cancer therapy. To determine the express