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The clinical role of the PEA3 transcription factor in ovarian and breast carcinoma in effusions

✍ Scribed by Ben Davidson; Iris Goldberg; Liora Tell; Sophya Vigdorchik; Mark Baekelandt; Aasmund Berner; Gunnar B. Kristensen; Reuven Reich; Juri Kopolovic

Book ID
111577284
Publisher
Springer
Year
2004
Tongue
English
Weight
323 KB
Volume
21
Category
Article
ISSN
0262-0898

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Expression of the PEA3 group of ETS-rela
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The PEA3 group of transcription factors belongs to the ets family and is composed of 3 known members, PEA3, ERM and ER81, which are more than 95% identical within the DNAbinding ETS domain and exhibit 50% aa identity overall. Recently, transgenic mice bearing the c-erbB-2/neu oncogene have been show