The clinical development of a 5α-reductase inhibitor, finasteride
✍ Scribed by Stoner, Elizabeth
- Book ID
- 122930324
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 357 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0960-0760
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a b s t r a c t Finasteride and epristeride both inhibit 5a-reductase with high potency via competitive and non-competitive mechanism, respectively. A new hybrid of finasteride and epristeride was designed as a new 5a-reductase inhibitor based on combination principles in medicinal chemistry. Human