𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The clinical and genetic manifestations of hereditary nonpolyposis colorectal carcinoma

✍ Scribed by John C. D'Emilia; Miguel A. Rodriguez-Bigas; Nicholas J. Petrelli

Book ID
117027355
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
752 KB
Volume
169
Category
Article
ISSN
0002-9610

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Clinical manifestations in patients with
Clinical manifestations in patients with hereditary nonpolyposis colorectal cancer
✍ Tomoda, Hirotsugu; Baba, Hideo; Oshiro, Tatsuo πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 408 KB πŸ‘ 2 views

The clinical manifestations of 1,042 Japanese patients with nonpolyposis colorectal cancer who underwent a resection between 1972 and 1992 at the National Kyushu Cancer Center were examined. Hereditary nonpolyposis colorectal cancer (HNPCC) was found in 39 (3.7%) patients. Some characteristic findin

Molecular genetics and hereditary cancer
Molecular genetics and hereditary cancer : Hereditary nonpolyposis colorectal carcinoma as a model
✍ Ramon Parsons πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 102 KB πŸ‘ 2 views

with the germline mutation of a DNA mismatch repair gene. Tumors from these Departments of Pathology and Medicine, Copatients typically exhibit microsatellite instability, which is a reflection of their lumbia University College of Physicians & Surlack of mismatch repair activity. The genetic diagno

Hereditary nonpolyposis colorectal cance
Hereditary nonpolyposis colorectal cancer: Review of clinical, molecular genetics, and counseling aspects
✍ Bellacosa, Alfonso; Genuardi, Maurizio; Anti, Marcello; Viel, Alessandra; de Leo πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 45 KB πŸ‘ 3 views

Lynch syndrome, or hereditary nonpolyposis colon cancer (HNPCC), is an autosomaldominant disease accounting for approximately 1 5 % of all colorectal cancer cases. Due to the lack of pathognomonic morphological or biomolecular markers, HNPCC has traditionally posed unique problems to clinicians and

Clinical impact of molecular genetic dia
Clinical impact of molecular genetic diagnosis, genetic counseling, and management of hereditary cancer : Part II: Hereditary nonpolyposis colorectal carcinoma as a model
✍ Henry T. Lynch; Patrice Watson; Trudy G. Shaw; Jane F. Lynch; Anne E. Harty; Bar πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 114 KB πŸ‘ 3 views

Hereditary nonpolyposis colorectal carcinoma (HNPCC) is the most common hereditary form of colorectal carcinoma (CRC) and may account for 5-10% of the total CRC burden. The discovery of DNA mismatch repair (MMR) genes, inclusive of hMSH2, hMLH1, hPMS2, and hMSH6, has enabled the identification of wh