The Cleavage of t-Butyldimethylsilyl Ethers with Boron Trifluoride Etherate
โ Scribed by Kelly, David R.; Roberts, Stanley M.; Newton, Roger F.
- Book ID
- 120307462
- Publisher
- Taylor and Francis Group
- Year
- 1979
- Tongue
- English
- Weight
- 145 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0039-7911
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
t\_Butyldimethylsilyl ethers are cleaved with sodium hydride in hexamethylphosphoric triamide (HMPA) or N ,N'-dimethylpropyleneurea (DMPU).
Mixtures consisting of five equivalents each of borane.methyl sulfide and boron trifluoride etherate per equivalent of acetal or five equivalents of various amine-borane complexes and 10 equivalents of boron trifluoride etherate readily accomplished reductive cleavage of the glycosidic linkages of s
Alkyl TBS ethers can be selectively cleaved in high yield in the presence of aryl TBS ethers employing either in situ generated hydrogen chloride or hydrogen iodide.