๐”– Bobbio Scriptorium
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The chromophore of viomycin

โœ Scribed by J.H. Bowie; A.W. Johnson; G. Thomas


Publisher
Elsevier Science
Year
1964
Tongue
French
Weight
163 KB
Volume
5
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


Bcceived 2 Uarch 1961) Acid hydrolysis of the strongly basic tuberculostatic antibiotic, vionycin 1.2 is known to yield L-swine, L-a~-diaminopropionic acid, L-B-lysine, carbon dioxide, ammonia, urea and a guanido compound. In a recent paper, 3IV er and hi8 collerguo~ suggeatad that the guanido compound, which was named viomycidine, vu 3-guanido-l-pyrrolino-2-


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Many attempts have been made to elucidate the structure of viomycin, P strongly basic tuberculostatic streptomyces antibiotic (l-7). These studies led Bowie, CoX,Johnson and Thomas (6) tc present I and more recently Dyer, Kellogg, Nassar and Streetman (7) to propose II as the structure of viomycin.

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