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The chemistry of vicinal tricarbonyls. Formation of oxomalondiamides

โœ Scribed by Harry H Wasserman; Kieseung Lee; Mingde Xia


Book ID
104210085
Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
166 KB
Volume
41
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


Oxomalondiamides and related systems are readily formed from derivatives of oxalic acid monoamides. The monoamides are converted to labile triacyl nitriles through cyano ylide intermediates for further coupling with amines and other nucleophiles.


๐Ÿ“œ SIMILAR VOLUMES


The chemistry of vicinal tricarbonyls a
โœ Harry H. Wasserman; Louis J. Lombardo ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 206 KB

The addition of primary amines to alkenyl vicinal tricarbonyls leads to Ssubstituted-3-hydroxypyrroles. This reaction has been employed in a synthesis of the 2formyl-3-methoxy-a,a'-bipyrrole precursor of the prodigiosin family of natural products.