## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
The chemistry of 2',3'-seconucleosides IV. Synthesis and reactions of 3'-azido-2',3'-dideoxy-2',3'- secothymidine and related analogues
✍ Scribed by Ajit Kumar; Richard T. Walker
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 625 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0040-4020
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The synthesis and antiviral evaluation of 2',3'-dideoxy and 2',3'-didehydro-2',3'-dideoxy 4'thionucleosides in both enantiomeric series are described. Enantiomeric 4-O-silylated-4hydroxymethyl-4-thiobutyrolactones, produced in high yield from chiral glycidols, provided suitable chiral synthons: phen
## Abstract The α,β‐unsaturated D‐sugar aldehyde 2, prepared from tri‐__O__‐acetyl‐D‐glucal, was converted into 1‐__O__‐acetyl‐3‐azido‐2,3‐dideoxy‐α‐D‐__arabino__‐pyranose (3) by reaction with sodium azide in a mixture of acetic acid and water followed by acetylation. Reaction of 3 with silylated p