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The chemical synthesis of the RP and SP diastereomers of thymidyl(3′-5′)thymidyl 0,0-phosphorothioate

✍ Scribed by Bogdan Uzna'nski; Wojciech Niewiarowski; Wojciech J. Stec


Book ID
104221995
Publisher
Elsevier Science
Year
1982
Tongue
French
Weight
259 KB
Volume
23
Category
Article
ISSN
0040-4039

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The synthesis of the Sp and Rp diastereo
✍ Yi Jin; George Just 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 173 KB

The diastereomers of thymidyl-(3'-5')thymidyl O,O-boranophosphate Sp-4 and Rp-4 were easily separated and transformed to title compounds Sp-7 and Rp-7. Their configurations were assigned by comparison with literature data.