𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The chemical synthesis of peptidomimetic libraries

✍ Scribed by Zuckermann, Ronald N.

Book ID
122888423
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
537 KB
Volume
3
Category
Article
ISSN
0959-440X

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Synthesis of oligopeptide and peptidomim
Synthesis of oligopeptide and peptidomimetic libraries
✍ Victor J Hruby; Jung-Mo Ahn; Subo Liao πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 English βš– 641 KB

The elaboration of peptide libraries prepared by either chemical or biological methods in a format useful for discovery of peptides with specific biological activities was first introduced in the 1980s. A virtual explosion of activity in this area has occurred recently, and the basic approaches have

The synthesis of peptidomimetic combinat
The synthesis of peptidomimetic combinatorial libraries through successive amide alkylations
✍ Barbara DΓΆrner; Gregory M. Husar; John M. Ostresh; Richard A. Houghten πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 686 KB

A soluble peptidomimetic combinatorial library of 57,500 compounds was prepared. This library has a dipeptide scaffold with each amide hydrogen replaced with five different alkyl groups (methyl, ethyl, allyl, benzyl, or naphthylmethyl). Solid-phase methodology in combination with N-alkylation were u