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The Characterization of the Common Fragile Site FRA16D and Its Involvement in Multiple Myeloma Translocations

โœ Scribed by Kurt A Krummel; Lewis R Roberts; Masako Kawakami; Thomas W Glover; David I Smith


Book ID
115615236
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
311 KB
Volume
69
Category
Article
ISSN
0888-7543

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Recently, several common fragile sites (CFSs) have been cloned and characterized, including the two most frequently observed in the human population, FRA3B and FRA16D. In addition to their high frequency of breakage, FRA3B and FRA16D colocalize with genes crossing large regions of breakage. At FRA3B