The characteristic binding of catechol estrogens to estrogen receptors in 7,12-dimethylbenz(a)anthraceneinduced rat mammary tumors
โ Scribed by Touichi Tanaka; Masakazu Katoh; Akiko Kubodera
- Book ID
- 116065086
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 409 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0039-128X
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The presence of ER in DMBA-tumors was demonstrated by the use of dextrancharcoal assay, sephadex chromatography, sucrose gradient sedimentation, and organ culture techniques. It was found that tumors have binding sites ranging from 10-" to 10-l' moles/mg protein, and a dissociation constant of ER 10
## Abstract The __PCPH__ protoโoncogene was identified by its frequent activation in Syrian hamster fetal cells exposed to 3โmethylcholanthrene. We previously isolated human __PCPH__ cDNA and studied its expression in normal human tissues. We report herein the pattern of __PCPH__ expression in norm