Complex heterocyclic structures - a chal
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K. Mueller; H. J. Ammann; D. M. Doran; P. R. Gerber; K. Gubernator; G. Schrepfer
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Article
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2010
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Wiley (John Wiley & Sons)
β 604 KB
Computer-assisted molecular modeling in the pharmaceutical research environment is repeatedly challenged to cope with diverse and often complex heterocyclic structures. Such systems may contain any type of strained fragments, unsaturated hetero-functionalities, heterorings with extended pi-conjugati