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The Cglycosyl analog of an N-linked glycoamino acid

✍ Scribed by R.Marshall Werner; Leonard M. Williams; Jeffery T. Davis


Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
235 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis


The synthesis of a new glycoamino acid deriwltive, a direct C-analog of N4-(2-acetamido-2-deoxy-~3 -D-glucopyranosyl)-L-Asn is described. The C-glycoside is prepared by a tandem Horner-Emmons-Wadsworth olefination-Michael addition between an aspartyl [3-keto phosphonate and a 4,6-O-benzylidene GIcNAc sugar.


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