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An Expeditious Synthesis of N-Acetylneuraminic Acid α-C-Glycosyl Derivatives (“α-C-Glycosides”) from the Anomeric Acetates.

✍ Scribed by Adeline Malapella; Anna Coslovi; Gilles Doisneau; Jean-Marie Beau


Publisher
John Wiley and Sons
Year
2007
Weight
27 KB
Volume
38
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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Samarium Diiodide Promoted C-Glycosylati
✍ Olivier Jarreton; Troels Skrydstrup; Juan-Félix Espinosa; Jesús Jiménez-Barbero; 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 223 KB 👁 2 views

The synthesis of the C-glycoside analogue of the disaccharide Man-(a1 32)Man has been achieved in a highly stereoselective and efficient manner employing an approach which closely parallels O-glycoside synthesis. The key step included the samarium diiodide reduction of mannosyl pyridylsulfone 18 in