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The Cerebral Cortex in Neurodegenerative and Neuropsychiatric Disorders. Experimental Approaches to Clinical Issues

✍ Scribed by David F. Cechetto, Nina Weishaupt

Publisher
Academic Press
Year
2016
Tongue
English
Leaves
316
Edition
1
Category
Library
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✦ Synopsis

The Cerebral Cortex in Neurodegenerative and Neuropsychiatric Disorders: Experimental Approaches to Clinical Issues focuses on how pre-clinical investigations are addressing the clinical issues surrounding the involvement of the cerebral cortex in selected conditions of the nervous system, including Alzheimer’s Disease, Parkinson’s, addiction, and cardiovascular dysregulation.

Each chapter is written by an expert in his/her field who provides a comprehensive review of the clinical manifestations of cortical involvement and experimental techniques currently available to tackle cortical issues in disease. Thus, this present title provides a link between cortical clinical problems and investigational approaches to help foster future research with high translational value.

  • Offers a comprehensive overview on the best available in vivo and in vitro models to study cortical involvement
  • Presents models and specific techniques that help to guide investigators in their choices on how to address research questions experimentally
  • Provides expert commentary and a perspective on future trends at the end of each chapter
  • Addresses translational advances and promising therapeutic options
  • Includes references to key articles for additional detailed study

✦ Table of Contents

Content:
Front Matter,Copyright,List of Contributors,Foreword,IntroductionEntitled to full textPart I: Introductory ChaptersChapter 1 - Anatomy of the Cerebral Cortex, Pages 3-36, K.S. Rockland
Chapter 2 - Cortical Plasticity in Response to Injury and Disease, Pages 37-56, N. Weishaupt
Chapter 3 - Imaging Approaches to Cerebral Cortex Pathology, Pages 57-80, R. Bartha, T.-Y. Lee
Chapter 4 - Alzheimer’s Disease, Pages 83-118, J.H.K. Tam, S.H. Pasternak
Chapter 5 - Vascular Dementia, Pages 119-139, D.G. Munoz, N. Weishaupt
Chapter 6 - Frontotemporal Dementia, Pages 141-175, A.E. Arrant, E.D. Roberson
Chapter 7 - Parkinson’s Disease and the Cerebral Cortex, Pages 177-193, D.F. Cechetto, M. Jog
Chapter 8 - Huntington Disease, Pages 195-221, E.H. Kim, N. Mehrabi, L.J. Tippett, H.J. Waldvogel, R.L.M. Faull
Chapter 9 - Cortical Manifestations in Amyotrophic Lateral Sclerosis, Pages 223-242, A.J. Moszczynski, M.J. Strong
Chapter 10 - Cortical Involvement in Multiple Sclerosis, Pages 243-273, P. Bannerman
Chapter 11 - Prefrontal Cortical Abnormalities in Cognitive Deficits of Schizophrenia, Pages 277-287, N. Rajakumar
Chapter 12 - Role of the Prefrontal Cortex in Addictive Disorders, Pages 289-309, J. Renard, L. Rosen, W.J. Rushlow, S.R. Laviolette
List of Acronyms and Abbreviations, Pages 311-314
Index, Pages 315-320

✦ Subjects

Nervous system;Degeneration;Neurobehavioral disorders;Cerebral cortex;Abnormalities;Medicine, Experimental;HEALTH & FITNESS;Diseases;General;MEDICAL;Clinical Medicine;MEDICAL;Diseases;MEDICAL;Evidence-Based Medicine;MEDICAL;Internal Medicine

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