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The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase

✍ Scribed by Shingo Toji; Norikazu Yabuta; Toshiya Hosomi; Souichi Nishihara; Toshiko Kobayashi; Susumu Suzuki; Katsuyuki Tamai; Hiroshi Nojima

Book ID
108589768
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
398 KB
Volume
9
Category
Article
ISSN
1356-9597

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## Abstract Aurora‐A is an oncogenic kinase that plays essential roles in mitosis as well as cell survival. Aurora‐A interacting protein (AIP) was identified as a negative regulator of Aurora‐A with its ectopic over expression inducing destabilization of Aurora‐A protein. Here we present evidence t