Dynamic association of a tumor amplified kinase, Aurora-A, with the centrosome and mitotic spindle

Subnuclear targeting of the Runx3 tumor

Subnuclear targeting of the Runx3 tumor suppressor and its epigenetic association with mitotic chromosomes

✍ Sandhya Pande; Syed A. Ali; Christopher Dowdy; Sayyed K. Zaidi; Kosei Ito; Yoshi 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 527 KB

## Abstract Runx proteins are tissue‐specific transcriptional scaffolds that organize and assemble regulatory complexes at strategic sites of target gene promoters and at intranuclear foci to govern activation or repression. During interphase, fidelity of intranuclear targeting supports the biologi