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The central role of the antigen-specific receptor complex in triggering cytolytic activity of cytotoxic T lymphocytes

✍ Scribed by Herman N. Eisen; Margaret A. Liu; David M. Kranz

Book ID
112484239
Publisher
Springer
Year
1985
Tongue
English
Weight
716 KB
Volume
5
Category
Article
ISSN
0144-8463

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A monoclonal antibody (CB.l) is described that defines a new triggering signal for human cytotoxic T lymphocytes (CTL). The antibody precipitates a 103-kDa surface antigen from activated normal human T cells. The antigen is undetectable or present in only low amounts on resting T lymphocytes but its