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The central role of CD30L/CD30 interactions in allergic rhinitis pathogenesis in mice

✍ Scribed by Takafumi Fuchiwaki; Xun Sun; Kenjiro Fujimura; Hisakata Yamada; Kensuke Shibata; Hiromi Muta; Eckhard R. Podack; Hideyuki Kawauchi; Yasunobu Yoshikai


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
409 KB
Volume
41
Category
Article
ISSN
0014-2980

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## Abstract CD30 is a costimulatory molecule of the TNF receptor superfamily, expressed on activated T and B cells. Previously, we have shown in a murine asthma model the crucial role of CD30 signaling for the development of this Th2‐cell‐mediated disease. In the present study, we investigated the