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The cellular response to general and programmed DNA double strand breaks

✍ Scribed by Craig H. Bassing; Frederick W. Alt


Book ID
116410318
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
522 KB
Volume
3
Category
Article
ISSN
1568-7864

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## Abstract DNA double‐strand breaks (DSBs) are the most hazardous lesions arising in the genome of eukaryotic organisms, and yet occur normally during DNA replication, meiosis, and immune system development. The efficient repair of DSBs is crucial in maintaining genomic integrity, cellular viabili