The cellular immune response against JC virus is instrumental in the containment of progressive multifocal leukoencephalopathy
โ Scribed by R. A. Du Pasquier; M. J. Kuroda; J. E. Schmitz; J. Jean-Jacques; Y. Zheng; N. L. Letvin; I. J. Koralnik
- Book ID
- 111739275
- Publisher
- Springer US
- Year
- 2004
- Tongue
- English
- Weight
- 62 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1355-0284
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๐ SIMILAR VOLUMES
## Abstract The kidneys of six progressive multifocal leukoencephalopathy (PML) patients were examined by PCR amplification for the presence of JC virus. Amplification of three different areas of the viral genome from multiple samples of each kidney revealed three that were positive for the virus.
Progressive multifocal leukoencephalopathy (PML), a viral-induced demyelinating disease, is becoming relatively common, while many diagnostic and pathogenetic aspects remain to be clarified. A study was therefore undertaken in 64 AIDS patients suffering from various neurological disorders, including