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The catechol-O-methyltransferase (COMT) gene polymorphism and prevalence of uterine fibroids

✍ Scribed by Emerson de Oliveira; Rodrigo de Aquino Castro; Mariano Tamura Vieira Gomes; Ismael Dale Cotrim Guerreiro da Silva; Edmund Chada Baracat; Geraldo Rodrigues de Lima; Marair Gracio Ferreira Sartori; Manoel João Batista Castello Girão

Book ID
116731771
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
163 KB
Volume
60
Category
Article
ISSN
0378-5122

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## Abstract High and low catechol‐__O__‐methyltransferase (COMT) activity is significantly determined by thermostability, which is caused by a valine/methionine~108~ polymorphism associated with polymorphic G/A~1947~ bases, in exon 4 of the COMT gene. Our allelic association study on this polymorph