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The carbohydrate units of asialo-ovomucoid: Structural features

✍ Scribed by James Conchie; Alister J. Hay; James A. Lomax

Publisher: Elsevier Science
Year: 1983
Tongue: English
Weight: 773 KB
Volume: 112
Category: Article
ISSN: 0008-6215
DOI: 10.1016/0008-6215(83)88292-5

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✦ Synopsis

The structural features of a heterogeneous glycopeptide fraction from asialoovomucoid have been investigated by methylation analysis of the fraction and of products obtained at each stage of its sequential degradation with exo-glycosidases. All glycopeptides in the fraction had a common core-structure f-D

Heterogeneity in the fraction arose from variation in the amount of terminal galactose attached via a hexosaminyl residue to the a-D-Manp-(1-*3) residue, and from limited variation in the number of terminal hexosaminyl groups attached to the a-D-Manp-(1-*6) residue . One glycopeptide in the fraction contained the unusual feature of two different, triply-substituted mannosyl residues . Other structural features of the glycopeptide are discussed .

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