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Structures of the carbohydrate moiety attached to one site in the first domain of turkey ovomucoid: Elucidation by 1H-N.M.R. spectroscopy

✍ Scribed by John M. Risley; Robert L. Van Etten


Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
748 KB
Volume
147
Category
Article
ISSN
0008-6215

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✦ Synopsis


H-N.m.r. spectroscopy was used to elucidate the primary structures of the carbohydrate moiety attached to asparagine at residue 53 in the first domain of turkey ovomucoid, a serine proteinase inhibitor. The carbohydrate moiety is a heterogeneous mixture of three structurally closely related complex-type oligosaccharides. Of the total carbohydrate moiety, 61% is tetra-antennary with terminal galactose and with an intersecting N-acetylglucosamine, and containing an additional N-acetylglucosamine (10') attached to mannose (4'). Another 23% is tri-antennary with terminal galactose and with an intersecting N-acetylglucosamine. The remaining 16% is tri-antennary with terminal galactose (6 and 8 only), with an intersecting ZV-acetylglucosamine.