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The candidate Wilms' tumour gene is involved in genitourinary development

✍ Scribed by Pritchard-Jones, Kathryn; Fleming, Stewart; Davidson, Duncan; Bickmore, Wendy; Porteous, David; Gosden, Christine; Bard, Jonathan; Buckler, Alan; Pelletier, Jerry; Housman, David

Book ID
109764194
Publisher
Nature Publishing Group
Year
1990
Tongue
English
Weight
714 KB
Volume
346
Category
Article
ISSN
0028-0836

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πŸ“œ SIMILAR VOLUMES

The Simpson-Golabi-Behmel gene,GPC3, is
The Simpson-Golabi-Behmel gene,GPC3, is not involved in sporadic Wilms tumorigenesis
✍ Gillan, Tanya L. ;Hughes, Rhiannon ;Godbout, Roseline ;Grundy, Paul E. πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 126 KB πŸ‘ 2 views

## Abstract Many genes have been implicated in Wilms tumor; however, only one gene, __WT1__, has a proven role in the development of this embryonal tumor. Wilms tumor occurs in a number of congenital syndromes including the Simpson–Golabi–Behmel syndrome (SGBS) which has phenotypic overlap with ano

The QM gene is X-linked and therefore no
The QM gene is X-linked and therefore not involved in suppression of tumorigenesis in Wilms' tumor
✍ Ans M. W. Ouweland; Marian Verdijk; Marcel M. A. M. Mannens; Bernard A. Oost πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 349 KB

Inactivation of one or more tumor-suppressor genes on the short arm of chromosome 11 is thought to play a role in the etiology of Wilms' tumor. A candidate gene, QM, was recently isolated by subtractive hybridization between a tumorigenic cell line (deleted for part of 11p) and a non-tumorigenic cel