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The c-terminal domain of the alpha subunit of Escherichia coli RNA polymerase is required for efficient rho-dependent transcription termination

✍ Scribed by Mark Kainz; Richard L Gourse


Book ID
115628899
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
756 KB
Volume
284
Category
Article
ISSN
0022-2836

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The Ξ± subunit C-terminal domain (Ξ±CTD) of RNA polymerase (RNAP) is a key element in transcription activation in__Escherichia coli__, possessing determinants responsible for the interaction of RNAP with DNA and with transcription factors. Here, the crystal structure of__E. coli__Ξ±CTD (Ξ± subunit resid