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The c-kit proto-oncogene in normal and malignant human hematopoiesis

✍ Scribed by Wariusz Z. Ratajczak; Selina M. Luger; Alan M. Gewirtz

Book ID
112212352
Publisher
AlphaMed Press
Year
1992
Tongue
English
Weight
864 KB
Volume
10
Category
Article
ISSN
1066-5099

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Human piebaldism: six novel mutations of
Human piebaldism: six novel mutations of the proto-oncogene KIT
✍ Petros Syrris; Kirsten Heathcote; Romeo Carrozzo; Koen Devriendt; Nursel ElΓ§iogl πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 127 KB

Human piebaldism is a rare autosomal dominant disorder that comprises congenital patchy depigmentation of the scalp, forehead, trunk and limbs. It is caused by mutations in the cell-surface receptor tyrosine kinase gene (KIT, also c-kit). We screened three families and three isolated cases of piebal