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The Btk subfamily of cytoplasmic tyrosine kinases: structure, regulation and function

✍ Scribed by David J. Rawlings*; Owen N. Witte*†

Book ID
115647793
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
98 KB
Volume
7
Category
Article
ISSN
1044-5323

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## Abstract Cytoplasmic protein‐tyrosine kinases (PTKs) are enzymes involved in transducing a vast number of signals in metazoans. The importance of the Tec family of kinases was immediately recognized when, in 1993, mutations in the gene encoding Bruton's tyrosine kinase (Btk) were reported to cau