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The Brain Entry of HIV-1 Protease Inhibitors Is Facilitated When Used in Combination

✍ Scribed by Marzolini, Catia; Mueller, Rita; Li-Blatter, Xiaochun; Battegay, Manuel; Seelig, Anna


Book ID
126776717
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
884 KB
Volume
10
Category
Article
ISSN
1543-8384

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The program DOCK [1,2] has been used successfully to identify molecules which will bind to a specified receptor [3]. The original method ranks molecules based on their shape complementarity to the receptor site and relies on the chemist to bring the appropriate electrostatic or hydrogen bond propert