HPLC quantification of the HIV-1 protease inhibitor saquinavir in brain and testis of mice
β Scribed by Koteshwara Mudigonda; Raju Jukanti; Shashank S. Apte; Devender R. Ajjala; Wishu Shrivastava; Vishwottam N. Kandikere; Ramakrishna V. S. Nirogi
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 79 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0269-3879
- DOI
- 10.1002/bmc.631
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does not contain a basic amine as do Saquinovir and JG-365, for example it should be easier to desolvate, which also assists in binding. The relationship between KNI-272, JG-365, Saquinovir, and P X proline-containing substrate also is 1
We report the development of a simple, economical and reliable chromatographic method for the simultaneous determination of six HIV protease inhibitors (PIs; amprenavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir), the active metabolite of nelfinavir (M8) and the non-nucleoside rever