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The blood picture of normal laboratory animals. A review the literature 1936–1946

✍ Scribed by Mary Virginia Gardner

Publisher
Elsevier Science
Year
1947
Tongue
English
Weight
236 KB
Volume
243
Category
Article
ISSN
0016-0032

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✦ Synopsis

THE GUINEA PIG, Guinea pigs are no longer the most commonly used laboratoryanimal as they probably were before 1930, when Scarborough (1) reviewed the literature on the blood picture of normal guinea pigs. For that reason fewer reports on guinea pig hematology have been appearing in the literature, particularly since 1940.

Method of Obtaining Blood. Blood sufficient for routine hematological examination may be obtained from the marginal ear vein of the guinea pig. When a larger quantity of blood is needed it may be procured by heart puncture.

Red Blood Cells. The erythrocyte of the guinea pig is a nonnucleated biconcave disc whichappearsorange in Wright-stained preparations. The average of the reported values for the number of erythrocytes in the blood of the adultguinea pig, regardless of sex, is 5,640,000 per cram. (Table I) "FABLE I.

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## THE MOUSE Not much information is available on the biood of normal mice, since these animals have been used very little in hematological work. Method of Obtaining Blood. Blood is usually obtained by incising the tail vein or by puncturing the heart. Repeated use of either method over a short p