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The biotransformation of isosorbide dinitrate in dogs and humans

✍ Scribed by Albert J. Dietz Jr.

Book ID: 115769529
Publisher: Elsevier Science
Year: 1967
Tongue: English
Weight: 149 KB
Volume: 16
Category: Article
ISSN: 0006-2952
DOI: 10.1016/0006-2952(67)90234-1

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## Abstract Plasma concentrations of isosorbide dinitrate have been measured after intravenous infusion of drug at a rate of 5·0 mg h^−1^ for 150 min and after single equal oral doses of 12·5 mg of drug in solution to two normal human subjects. During the infusion, uneven plateau concentrations wer