It could be shown that Streptomyces griseus, the microorganism producing the antibiotic streptomycin and also mutant strains of this species that cannot synthesize streptomycin, possess myo-inositol-1-phosphate synthase (EC 5.5.1.4), the enzyme cyclizing D-glucose 6-phosphate. The enzyme isolated fr
The Biosynthesis of Cyclitols
β Scribed by Dr. H. Kindl; R. Scholda; Prof. Dr. O. Hoffmann-Ostenhof
- Publisher
- John Wiley and Sons
- Year
- 1966
- Tongue
- English
- Weight
- 863 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0044-8249
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## Abstract The gene __valC__, which encodes an enzyme homologous to the 2β__epi__β5β__epi__βvaliolone kinase (AcbM) of the acarbose biosynthetic pathway, was identified in the validamycin A biosynthetic gene cluster. Inactivation of __valC__ resulted in mutants that lack the ability to produce val