𝔖 Bobbio Scriptorium
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The Biosynthesis and Catabolism of the Maleic Anhydride Moiety of Stipitatonic Acid

✍ Scribed by al Fahad, Ahmed; Abood, Amira; Simpson, Thomas J.; Cox, Russell J.


Book ID
121879039
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
964 KB
Volume
53
Category
Article
ISSN
0044-8249

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A Novel Route to the Fused Maleic Anhydr
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A seven-step cascade reaction-in which selective mesylation, epoxide formation, epoxide lysis, cyclization, reiterative oxidation, and nitrogen-oxygen exchange occur sequentially-facilitates the construction of the maleic anhydride moiety of CP molecules 1 and 2 (>93% yield per step). Unstable inter